Nipple changes Nipple changes Breast and nipple changes can be a sign of breast cancer. Make an appointment with your doctor if you notice anything unusual. Signs and symptoms of breast cancer may include: A breast lump or thickening that feels different from the surrounding tissue Change in the size, shape or appearance of a breast Changes to the skin over the breast, such as dimpling A newly inverted nipple Peeling, scaling, crusting or flaking of the pigmented area of skin surrounding the nipple areola or breast skin Redness or pitting of the skin over your breast, like the skin of an orange When to see a doctor If you find a lump or other change in your breast — even if a recent mammogram was normal — make an appointment with your doctor for prompt evaluation. Request an Appointment at Mayo Clinic Causes Doctors know that breast cancer occurs when some breast cells begin to grow abnormally.
Breast Cancer in Women
Breast cancer - Symptoms and causes - Mayo Clinic
What Is HER2? HER2 proteins are present on the surface of some breast cancer cells. Normally, HER2 proteins regulate and control the growth of breast cells. But when the HER2 gene is mutated, which is the case in about 1 in every 5 cases of breast cancer, it makes too many HER2 proteins. This results in breast cells growing and dividing out of control. Why should I have HER2 testing?
Genes contain the recipes for the various proteins a cell needs to stay healthy and function normally. Some genes and the proteins they make can influence how a breast cancer behaves and how it might respond to a specific treatment. Cancer cells from a tissue sample can be tested to see which genes are normal and abnormal. The proteins they make can also be tested. HER2 proteins are receptors on breast cells.
The publisher's final edited version of this article is available at Med Sci Turkey See other articles in PMC that cite the published article. Abstract CerbB2 receptor determination is very important for the prognosis and treatment of breast cancer. Our study compared these two groups in terms of relaps duration. The relaps duration of the patients were determined and then compared statistically. Similarly, when the immunohistochemical tests and FISH tests are compared for CerbB2 positivity, different results are obtained.